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pt</tps:fontSize> <tps:leading>14 pt</tps:leading> <tps:color> PANTONE 286 CVC </tps:color> </tps:charStyleDef> </tps:charStyle> <tps:spaceBefore>4.23333 mm</tps:spaceBefore> <tps:spaceAfter>0.511528 mm</tps:spaceAfter> <tps:nextStyle>Heading_1</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Heading_2</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Heading_2</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>10 pt</tps:fontSize> <tps:leading>12 pt</tps:leading> <tps:color> PANTONE 286 CVC </tps:color> </tps:charStyleDef> </tps:charStyle> <tps:alignment>center</tps:alignment> <tps:spaceBefore>4.23333 mm</tps:spaceBefore> <tps:spaceAfter>0.511528 mm</tps:spaceAfter> <tps:nextStyle>Heading_2</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Discussion Heading</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Discussion Heading</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>10 pt</tps:fontSize> <tps:leading>12 pt</tps:leading> <tps:color> PANTONE 286 CVC </tps:color> </tps:charStyleDef> </tps:charStyle> <tps:alignment>center</tps:alignment> <tps:spaceBefore>3.175 mm</tps:spaceBefore> <tps:spaceAfter>1.5875 mm</tps:spaceAfter> <tps:nextStyle>Discussion Heading</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Conflict of Interest Head</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Conflict of Interest Head</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>10 pt</tps:fontSize> <tps:leading>12 pt</tps:leading> <tps:color> PANTONE 286 CVC </tps:color> </tps:charStyleDef> </tps:charStyle> <tps:alignment>center</tps:alignment> <tps:spaceBefore>3.175 mm</tps:spaceBefore> <tps:spaceAfter>1.5875 mm</tps:spaceAfter> <tps:nextStyle>Conflict of Interest Head</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Conflict of Interest</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Conflict of Interest</tps:name> <tps:font/> <tps:fontSize>10 pt</tps:fontSize> <tps:leading>12 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentFirstLine>3.175 mm</tps:indentFirstLine> <tps:spaceBefore>1.5875 mm</tps:spaceBefore> <tps:nextStyle>Conflict of Interest</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Author Affiliations</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Author Affiliations</tps:name> <tps:font/> <tps:fontSize>8.5 pt</tps:fontSize> <tps:leading>9.5 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>1.5875 mm</tps:indentLeft> <tps:indentFirstLine>-1.5875 mm</tps:indentFirstLine> <tps:spaceBefore>3.175 mm</tps:spaceBefore> <tps:nextStyle>Author Affiliations</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Corresponding Author</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Corresponding Author</tps:name> <tps:font/> <tps:fontSize>8.5 pt</tps:fontSize> <tps:leading>9.5 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>1.5875 mm</tps:indentLeft> <tps:spaceBefore>1.5875 mm</tps:spaceBefore> <tps:nextStyle>Corresponding Author</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Summary Box Ttile</tps:name> <tps:basedOn>Figure Title</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>Summary Box Ttile</tps:name> <tps:basedOn>Figure Title</tps:basedOn> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:spaceAfter>1.5875 mm</tps:spaceAfter> <tps:nextStyle>Summary Box Heading</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Summary Box Heading</tps:name> <tps:basedOn>Summary Box Text</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>Summary Box Heading</tps:name> <tps:basedOn>Summary Box Text</tps:basedOn> <tps:leading>9 pt</tps:leading> <tps:color> PANTONE 286 CVC </tps:color> </tps:charStyleDef> </tps:charStyle> <tps:spaceAfter>1.05833 mm</tps:spaceAfter> <tps:nextStyle>Summary Box Text</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Summary Box Text</tps:name> <tps:basedOn>Paragraph</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>Summary Box Text</tps:name> <tps:basedOn>Paragraph</tps:basedOn> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>9 pt</tps:fontSize> <tps:leading>11 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left</tps:alignment> <tps:indentFirstLine>0 mm</tps:indentFirstLine> <tps:spaceAfter>2.11667 mm</tps:spaceAfter> <tps:nextStyle>Summary Box Heading</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Ref_Title</tps:name> <tps:basedOn>Discussion Heading</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>Ref_Title</tps:name> <tps:basedOn>Discussion Heading</tps:basedOn> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:nextStyle>Ref_Title</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>References</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>References</tps:name> <tps:font/> <tps:fontSize>9 pt</tps:fontSize> <tps:leading>10 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>3.175 mm</tps:indentLeft> <tps:indentFirstLine>-3.175 mm</tps:indentFirstLine> <tps:nextStyle>References</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Reference_10</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Reference_10</tps:name> <tps:font/> <tps:fontSize>9 pt</tps:fontSize> <tps:leading>10 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>4.7625 mm</tps:indentLeft> <tps:indentFirstLine>-4.7625 mm</tps:indentFirstLine> <tps:nextStyle>Reference_10</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Reference_100</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Reference_100</tps:name> <tps:font/> <tps:fontSize>9 pt</tps:fontSize> <tps:leading>11 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>6.35 mm</tps:indentLeft> <tps:indentFirstLine>-6.35 mm</tps:indentFirstLine> <tps:nextStyle>Reference_100</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Acknowledgment_Head</tps:name> <tps:basedOn>Discussion Heading</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>Acknowledgment_Head</tps:name> <tps:basedOn>Discussion Heading</tps:basedOn> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:nextStyle>Acknowledgment_Head</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Acknowledgment</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Acknowledgment</tps:name> <tps:font/> <tps:fontSize>10 pt</tps:fontSize> <tps:leading>12 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentFirstLine>3.175 mm</tps:indentFirstLine> <tps:nextStyle>Acknowledgment</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Footnote</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Footnote</tps:name> <tps:font/> <tps:fontSize>8.5 pt</tps:fontSize> <tps:leading>9.5 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>1.5875 mm</tps:indentLeft> <tps:indentFirstLine>-1.5875 mm</tps:indentFirstLine> <tps:spaceBefore>3.175 mm</tps:spaceBefore> <tps:nextStyle>Footnote</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>footnote w/rule text indent 2</tps:name> <tps:basedOn>Footnote</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>footnote w/rule text indent 2</tps:name> <tps:basedOn>Footnote</tps:basedOn> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>3.175 mm</tps:indentLeft> <tps:indentFirstLine>-3.175 mm</tps:indentFirstLine> <tps:nextStyle>footnote w/rule text indent 2</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>footnote w/rule text indent 3</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>footnote w/rule text indent 3</tps:name> <tps:font/> <tps:fontSize>8.5 pt</tps:fontSize> <tps:leading>9.5 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>4.7625 mm</tps:indentLeft> <tps:indentFirstLine>-4.7625 mm</tps:indentFirstLine> <tps:nextStyle>footnote no rule text indent 1</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>footnote w/rule text indent 4</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>footnote w/rule text indent 4</tps:name> <tps:font/> <tps:fontSize>8.5 pt</tps:fontSize> <tps:leading>9.5 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>6.35 mm</tps:indentLeft> <tps:indentFirstLine>-6.35 mm</tps:indentFirstLine> <tps:nextStyle>Footnote</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>footnote no rule text indent 1</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>footnote no rule text indent 1</tps:name> <tps:font/> <tps:fontSize>8.5 pt</tps:fontSize> <tps:leading>9.5 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>1.60514 mm</tps:indentLeft> <tps:indentFirstLine>-1.60514 mm</tps:indentFirstLine> <tps:nextStyle>footnote no rule text indent 1</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>footnote no rule text indent 2</tps:name> <tps:basedOn>footnote no rule text indent 1</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>footnote no rule text indent 2</tps:name> <tps:basedOn>footnote no rule text indent 1</tps:basedOn> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>3.175 mm</tps:indentLeft> <tps:indentFirstLine>-3.175 mm</tps:indentFirstLine> <tps:nextStyle>footnote no rule text indent 2</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>footnote no rule text indent 3</tps:name> <tps:basedOn>footnote no rule text indent 1</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>footnote no rule text indent 3</tps:name> <tps:basedOn>footnote no rule text indent 1</tps:basedOn> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>4.78014 mm</tps:indentLeft> <tps:indentFirstLine>-4.78014 mm</tps:indentFirstLine> <tps:nextStyle>footnote no rule text indent 3</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>footnote no rule text indent 4</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>footnote no rule text indent 4</tps:name> <tps:font/> <tps:fontSize>8.5 pt</tps:fontSize> <tps:leading>9.5 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>6.35 mm</tps:indentLeft> <tps:indentFirstLine>-6.35 mm</tps:indentFirstLine> <tps:nextStyle>footnote no rule text indent 1</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Figure Title</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Figure Title</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>9 pt</tps:fontSize> <tps:leading>10 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:nextStyle>Figure Title</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Table_Title</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Table_Title</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>9 pt</tps:fontSize> <tps:leading>10 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:spaceAfter>1.5875 mm</tps:spaceAfter> <tps:nextStyle>Table_Title</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Box_Title</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Box_Title</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>9 pt</tps:fontSize> <tps:leading>10 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:nextStyle>Box_Title</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data 8pt semibold centered</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>table data 8pt semibold centered</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>center</tps:alignment> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>second level column head</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>second level column head</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>center</tps:alignment> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data ages</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>table data ages</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:nextStyle>table data ages</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Table_Body</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Table_Body</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data indent 1</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>table data indent 1</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>1.524 mm</tps:indentLeft> <tps:indentFirstLine>-1.524 mm</tps:indentFirstLine> <tps:nextStyle>table data indent 1</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data indent 2</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>table data indent 2</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>3.048 mm</tps:indentLeft> <tps:indentFirstLine>-1.524 mm</tps:indentFirstLine> <tps:nextStyle>table data indent 2</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data indent 3</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>table data indent 3</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>4.572 mm</tps:indentLeft> <tps:indentFirstLine>-1.524 mm</tps:indentFirstLine> <tps:nextStyle>table data indent 3</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data indent 4</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>table data indent 4</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>6.096 mm</tps:indentLeft> <tps:indentFirstLine>-1.524 mm</tps:indentFirstLine> <tps:nextStyle>table data indent 4</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data indent 5</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>table data indent 5</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>7.62 mm</tps:indentLeft> <tps:indentFirstLine>-1.524 mm</tps:indentFirstLine> <tps:nextStyle>table data indent 5</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data indent 6</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>table data indent 6</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>9.144 mm</tps:indentLeft> <tps:indentFirstLine>-1.524 mm</tps:indentFirstLine> <tps:nextStyle>table data indent 6</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data indent 7</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>table data indent 7</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>10.668 mm</tps:indentLeft> <tps:indentFirstLine>-1.524 mm</tps:indentFirstLine> <tps:nextStyle>table data indent 7</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data 8pt see page number</tps:name> <tps:basedOn>Table_Body</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>table data 8pt see page number</tps:name> <tps:basedOn>Table_Body</tps:basedOn> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:nextStyle>table data 8pt see page number</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Figure Footnote</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Figure Footnote</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>1.778 mm</tps:indentLeft> <tps:indentFirstLine>-1.778 mm</tps:indentFirstLine> <tps:nextStyle>Figure Footnote</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>8pt footnote supports indent 1</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>8pt footnote supports indent 1</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>1.778 mm</tps:indentLeft> <tps:indentFirstLine>-1.778 mm</tps:indentFirstLine> <tps:nextStyle>8pt footnote supports indent 1</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>8pt footnote supports indent 2</tps:name> <tps:basedOn>Figure Footnote</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>8pt footnote supports indent 2</tps:name> <tps:basedOn>Figure Footnote</tps:basedOn> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>3.175 mm</tps:indentLeft> <tps:indentFirstLine>-3.175 mm</tps:indentFirstLine> <tps:nextStyle>8pt footnote supports indent 2</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>8pt footnote supports indent 3</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>8pt footnote supports indent 3</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>4.23333 mm</tps:indentLeft> <tps:indentFirstLine>-4.23333 mm</tps:indentFirstLine> <tps:nextStyle>Figure Footnote</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>8pt footnote supports indent 4</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>8pt footnote supports indent 4</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>5.29167 mm</tps:indentLeft> <tps:indentFirstLine>-5.29167 mm</tps:indentFirstLine> <tps:nextStyle>Figure Footnote</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>8pt footnote supports indent 5</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>8pt footnote supports indent 5</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>6.477 mm</tps:indentLeft> <tps:indentFirstLine>-6.35 mm</tps:indentFirstLine> <tps:nextStyle>Figure Footnote</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>8pt footnote supports indent 6</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>8pt footnote supports indent 6</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>7.62 mm</tps:indentLeft> <tps:indentFirstLine>-7.62 mm</tps:indentFirstLine> <tps:nextStyle>Figure Footnote</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Abbreviations</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Abbreviations</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Early Release Disclaimer</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Early Release Disclaimer</tps:name> <tps:font> <tps:name>Adobe Garamond Pro</tps:name> <tps:style>Italic</tps:style> </tps:font> <tps:fontSize>11 pt</tps:fontSize> <tps:leading>13 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentFirstLine>3.175 mm</tps:indentFirstLine> <tps:nextStyle>Early Release Disclaimer</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Kicker</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Kicker</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold Italic</tps:style> </tps:font> <tps:fontSize>16 pt</tps:fontSize> <tps:leading>14 pt</tps:leading> <tps:color> PANTONE 286 CVC </tps:color> </tps:charStyleDef> </tps:charStyle> <tps:spaceAfter>5.08 mm</tps:spaceAfter> <tps:nextStyle>Kicker</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Head below Kicker</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Head below Kicker</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>12 pt</tps:fontSize> <tps:leading>14 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:spaceBefore>2.54 mm</tps:spaceBefore> <tps:spaceAfter>1.27 mm</tps:spaceAfter> <tps:nextStyle>Head below Kicker</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>qs figure title</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>qs figure title</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>14 pt</tps:fontSize> <tps:leading>16 pt</tps:leading> <tps:color> PANTONE 286 CVC </tps:color> </tps:charStyleDef> </tps:charStyle> <tps:alignment>center</tps:alignment> <tps:indentLeft>12.7 mm</tps:indentLeft> <tps:indentRight>12.7 mm</tps:indentRight> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>qs text 9 pt</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>qs text 9 pt</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>9 pt</tps:fontSize> <tps:leading>11 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>12.7 mm</tps:indentLeft> <tps:indentRight>12.7 mm</tps:indentRight> <tps:spaceBefore>4.23333 mm</tps:spaceBefore> <tps:spaceAfter>1.05833 mm</tps:spaceAfter> <tps:nextStyle>qs text 9 pt</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>qs source first</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>qs source first</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>10 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>12.7 mm</tps:indentLeft> <tps:indentRight>12.7 mm</tps:indentRight> <tps:spaceBefore>1.05833 mm</tps:spaceBefore> <tps:nextStyle>qs source first</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>qs source others</tps:name> <tps:basedOn>qs source first</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>qs source others</tps:name> <tps:basedOn>qs source first</tps:basedOn> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:spaceBefore>0.762 mm</tps:spaceBefore> <tps:nextStyle>qs source others</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Committee/Workgroup Title</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Committee/Workgroup Title</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Semibold</tps:style> </tps:font> <tps:fontSize>10 pt</tps:fontSize> <tps:leading>12 pt</tps:leading> <tps:color> PANTONE 286 CVC </tps:color> </tps:charStyleDef> </tps:charStyle> <tps:alignment>center</tps:alignment> <tps:spaceBefore>3.175 mm</tps:spaceBefore> <tps:spaceAfter>1.5875 mm</tps:spaceAfter> <tps:nextStyle>Committee/Workgroup Title</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Committee/Workgroup Names</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Committee/Workgroup Names</tps:name> <tps:font/> <tps:fontSize>10 pt</tps:fontSize> <tps:leading>12 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentFirstLine>3.175 mm</tps:indentFirstLine> <tps:nextStyle>Committee/Workgroup Names</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>disclosure head</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>disclosure head</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style>Bold</tps:style> </tps:font> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>center</tps:alignment> <tps:spaceBefore>2.11667 mm</tps:spaceBefore> <tps:nextStyle>disclosure head</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>disclosure text</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>disclosure text</tps:name> <tps:font/> <tps:fontSize>10 pt</tps:fontSize> <tps:leading>12 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentFirstLine>3.29847 mm</tps:indentFirstLine> <tps:spaceBefore>1.5875 mm</tps:spaceBefore> <tps:nextStyle>disclosure text</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>vital signs abstract text</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>vital signs abstract text</tps:name> <tps:font/> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:spaceAfter>1.27 mm</tps:spaceAfter> <tps:nextStyle>vital signs abstract text</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>body copy</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>body copy</tps:name> <tps:font/> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentFirstLine>3.175 mm</tps:indentFirstLine> <tps:nextStyle>body copy</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>body text left</tps:name> <tps:basedOn>body copy</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>body text left</tps:name> <tps:basedOn>body copy</tps:basedOn> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentFirstLine>0 mm</tps:indentFirstLine> <tps:nextStyle>body text left</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>bullet</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>bullet</tps:name> <tps:font/> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>6.35 mm</tps:indentLeft> <tps:indentFirstLine>-3.175 mm</tps:indentFirstLine> <tps:nextStyle>bullet</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>box subhead</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>box subhead</tps:name> <tps:font> <tps:name/> <tps:style>Bold</tps:style> </tps:font> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:spaceBefore>1.5875 mm</tps:spaceBefore> <tps:nextStyle>box subhead</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>bullet in a box</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>bullet in a box</tps:name> <tps:font/> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>3.175 mm</tps:indentLeft> <tps:indentFirstLine>-3.175 mm</tps:indentFirstLine> <tps:nextStyle>bullet in a box</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>bullet-2 in a box</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>bullet-2 in a box</tps:name> <tps:font/> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:indentLeft>7.76111 mm</tps:indentLeft> <tps:indentFirstLine>-3.52778 mm</tps:indentFirstLine> <tps:nextStyle>bullet-2 in a box</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data 8pt</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>table data 8pt</tps:name> <tps:font> <tps:name>Myriad Pro</tps:name> <tps:style/> </tps:font> <tps:fontSize>8 pt</tps:fontSize> <tps:leading>9 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>List_BUL</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>List_BUL</tps:name> <tps:font/> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>6.35 mm</tps:indentLeft> <tps:indentFirstLine>-3.175 mm</tps:indentFirstLine> <tps:nextStyle>List_BUL</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>List_BUL 2</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>List_BUL 2</tps:name> <tps:font/> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:alignment>left justify</tps:alignment> <tps:indentLeft>10.795 mm</tps:indentLeft> <tps:indentFirstLine>-3.81 mm</tps:indentFirstLine> <tps:nextStyle>List_BUL 2</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>---------------------------------------------</tps:name> <tps:basedOn>Committee/Workgroup Names</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>---------------------------------------------</tps:name> <tps:basedOn>Committee/Workgroup Names</tps:basedOn> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:nextStyle>---------------------------------------------</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>table data 8pt semibold left</tps:name> <tps:basedOn>Table_Body</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>table data 8pt semibold left</tps:name> <tps:basedOn>Table_Body</tps:basedOn> <tps:font> <tps:name/> <tps:style>Semibold</tps:style> </tps:font> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:nextStyle>table data 8pt semibold left</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Base_Heading</tps:name> <tps:charStyle> <tps:charStyleDef> <tps:name>Base_Heading</tps:name> <tps:font> <tps:name>Calibri</tps:name> <tps:style>Bold</tps:style> </tps:font> <tps:fontSize>14 pt</tps:fontSize> <tps:leading>0 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:spaceBefore>4.23333 mm</tps:spaceBefore> <tps:spaceAfter>2.82222 mm</tps:spaceAfter> <tps:nextStyle>Base_Heading</tps:nextStyle> </tps:parStyleDef> </tps:definition> <tps:definition tag="parStyleDef"> <tps:parStyleDef> <tps:name>Summary Box Title</tps:name> <tps:basedOn>Base_Heading</tps:basedOn> <tps:charStyle> <tps:charStyleDef> <tps:name>Summary Box Title</tps:name> <tps:basedOn>Base_Heading</tps:basedOn> <tps:fontSize>12 pt</tps:fontSize> <tps:leading>10 pt</tps:leading> </tps:charStyleDef> </tps:charStyle> <tps:nextStyle>Summary Box Title</tps:nextStyle> </tps:parStyleDef> </tps:definition> <!-- ======================= --> <!-- Table Style Definitions --> <!-- ======================= --> <tps:definition tag="tableStyleDef"> <tps:tableStyleDef> <tps:name>data table</tps:name> </tps:tableStyleDef> </tps:definition> <tps:definition tag="tableStyleDef"> <tps:tableStyleDef> <tps:name>fb table</tps:name> </tps:tableStyleDef> </tps:definition> <tps:definition tag="tableStyleDef"> <tps:tableStyleDef> <tps:name>regimen table</tps:name> </tps:tableStyleDef> </tps:definition> <tps:definition tag="tableStyleDef"> <tps:tableStyleDef> <tps:name>box</tps:name> </tps:tableStyleDef> </tps:definition> <!-- ================================== --> <!-- Cross-reference Format Definitions --> <!-- ================================== --> <tps:definition tag="crossRefFormatDef"> <tps:crossRefFormatDef> <tps:name>Full Paragraph &amp; Page Number</tps:name> </tps:crossRefFormatDef> </tps:definition> <tps:definition tag="crossRefFormatDef"> <tps:crossRefFormatDef> <tps:name>Full Paragraph</tps:name> </tps:crossRefFormatDef> </tps:definition> <tps:definition tag="crossRefFormatDef"> <tps:crossRefFormatDef> <tps:name>Paragraph Text &amp; Page Number</tps:name> </tps:crossRefFormatDef> </tps:definition> <tps:definition tag="crossRefFormatDef"> <tps:crossRefFormatDef> <tps:name>Paragraph Text</tps:name> </tps:crossRefFormatDef> </tps:definition> <tps:definition tag="crossRefFormatDef"> <tps:crossRefFormatDef> 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